Medicine
Doribax ® Doripenem 500 mg vial [Janssen-Cilag] Class: Carbapenem antibiotics NED & NC –Imipenem & Meropenem : ED ง Dosing: 500 mg iv q 8 hr (1 or 4 hr infusion)
Maharaj NST Antibiogram 2009 Drugs Organisms LocationAMKGENCROCAZCIPLVXTZPCSLIPMMEMCL A.baumannii IPD IPD MDR NEO PED SUR ORTHO ICU ICU MED MED
Maharaj NST Antibiogram 2009 Drugs Organisms LocationAMKGENCROCAZCIPLVXTZPCSLIPMMEMCL P.aeruginosa IPD IPD MDR NEO PED SUR ORTHO ICU ICU MED MED
Maharaj NST Antibiogram 2009 Drugs Organisms LocationAMKGENCROCAZCIPLVXTZPCSLIPMMEMCL E.coli IPD NEO PED SUR ORTHO ICU ICU MED MED E.coli ESBL+ IPD E.coli ESBL+ MDR IPD
Maharaj NST Antibiogram 2009 Drugs Organisms LocationAMKGENCROCAZCIPLVXTZPCSLIPMMEMCL K.pneumoniae IPD NEO PED SUR ORTHO ICU ICU MED MED K.pneumoniae ESBL+ IPD K.pneumoniae ESBL+ MDR IPD
IndicationsDoripenemImipenemMeropenem Bacterial septicemia - Genital inf., female - Bone & joint inf. - - Skin & soft tissue inf. - Intra-abdominal inf. IE- - LRI (VAP) Mixed inf.- UTI Meningitis-- Febrile neutropenia -- Surgical prophylaxis - -
DosingDoripenemImipenemMeropenem Intra-abdo inf, complicated 500 mg iv q 8 hr mg iv q 6-8 hr 1000 mg iv q 8 hr LRI included VAP 500 mg iv q 8 hr mg iv q 6-8 hr mg iv q 8 hr UTI included pyelo- nephritis 500 mg iv q 8 hr 500 mg iv q 6 hr 500 mg iv q 8 hr
SafetyDoripenemImipenemMeropenem Pediatric useX Dosage adjustment in renal insuff. Dosage adjustment in hepatic insuff. XXX Pregnancy cat.BCB Phlebitis - Diarrhea Nausea Anemia -- Agranulocytosis-- Seizure Renal failure -
Cost (Baht) Cost/ unit Cost/day Cost/ treatment course 8 days (VAP) 14 days Doripenem (500 mg iv q 8 hrs) Imipenem (1000 mg iv q 6 hrs) Meropenem (1000 mg iv q 8 hrs)
Micromedex Healthcare Series Online MIMS Thailand Online National List of Essential Medicines 2008 Product information (package insert) References