Overskrift 40/42 pkt, Maks 2 linjer Underoverskrift, 14/16 pkt For at vise hjælpelinjer: 1.Højreklik på slidet og vælg “Gitter og hjælpelinjer” 2.Kryds for “Vis hjælpelinjer på skærmen” 3. Vælg “OK” Company-initiated clinical trials in Denmark in 2013 Based on a survey among members of DANSK BIOTEK (Danish Association of Biotechnology Industries and Lif (Danish Association of the Pharmaceutical Industry).

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Trend in the number of trials for Lif companies Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Stagnation in the number of company-initiated clinical trials in Denmark DANSK BIOTEK and Lif's members carried out a total of 296 clinical trials in 2013 – 99 of which were new trials. The stabilisation noted in 2012 thus continued into 2013.

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Trials conducted under the aegis of CROs 73 trials were conducted under the aegis of external CROs* in After a marked increase between 2011 and 2012 (50 to 82), numbers of this type of trial have now again dropped back slightly. Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013 *Contract Research Organisations

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau In 2013, a total of 16,249 individuals participated in clinical trials in Denmark. This was significantly down on the previous three years when the number of trial subjects was more stable. The drop was also due to an increase in the proportion of early stage trials in which not so many subjects usually participate. Early stage trials are increasing, especially for cancer. Drop in numbers of trial subjects Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Trend in numbers of trial subjects Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013 * ** * This year’s counting does not include patients participating in clinical trials taking place under the auspices of external CROs.

Billedets format: H. 9,67 x B. 11,25 cm Number of personnel engaged in clinical research 1,854 full-time internal company personnel were engaged in clinical research in 2013, slightly up on previous years. 198 of these were engaged in clinical research carried out in Denmark. This was down on the 225 reported in A further 55 full-time personnel were engaged in clinical research in Denmark via external CROs. This was in line with Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in ,854 personnel.

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Expenditure on clinical trials External expenditure by members of DANSK BIOTEK and Lif were in total DKK 212.4m in 2013 for research primarily done by the national health service. This was markedly down on The stability noted since 2010 has now been replaced by a decline. Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Distribution of expenditure on clinical research in 2013 External spending on clinical trials managed and conducted by Lif and DANSK BIOTEK’s member companies totalled DKK 157.6m. Added to this external expenditure via CROs on fees and contributions to hospitals/university institutions, research foundations, investigators, lab reports, etc., totalled DKK 21.9m. DKK 32.9m was spent on investigator-initiated trials. Total external spending amounted to DKK 212.4m Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Clinical studies on children: General increase since 2009

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau Number of non-intervention trials is stable Source: Lif and DANSK BIOTEK’s survey of clinical research activities in Denmark in 2013

Sektion-slide Brug dette slide, når der kommer et nyt emne i præsentationen Find all the reports at Lif.dkLif.dk

Tekst starter uden punktopstilling For at få punkt- opstilling på teksten (flere niveauer findes), brug forøg listeniveau For at få venstrestillet tekst uden punktopstilling, brug formindsk listeniveau The Infographic can be downloaded from lif.dk (only in Danish)