Basics of pain research Abhishek Kumar and Lilja K. Dagsdóttir (PhD Scholars) Section of Clinical Oral Physiology Department of Dentistry, Aarhus University,

Præsentationer af emnet: "Basics of pain research Abhishek Kumar and Lilja K. Dagsdóttir (PhD Scholars) Section of Clinical Oral Physiology Department of Dentistry, Aarhus University,"— Præsentationens transcript:

1 Basics of pain research Abhishek Kumar and Lilja K. Dagsdóttir (PhD Scholars) Section of Clinical Oral Physiology Department of Dentistry, Aarhus University, Vennelyst Boulevard 9 Aarhus, Denmark

2 What is pain?  Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage *  Warning signal of tissue damage  Classified broadly into acute and chronic pain * International Association for the Study of Pain

3 Basic mechanisum of pain  Nociceptors : Specialised sensory receptors to detect noxious stimuli.  Spinal chord  Primary afferent fibres: carry noxious sensory information  Ascending pathway: carry nociceptive signals to higher centers in the brain  Brain: primary and secondary somatosensory cortex

4  The experience of pain is complex and subjective, and is affected by factors such as cognition (e.g., distraction or catastrophizing), mood, beliefs and genetics Perception of pain

5  Sensory organ for receiving inputs  The brain assimilates and organizes the sensory inputs Multisensory inputs

6 ↘ ↘ ↘ ↘ Case report

7 Pain in Laboratory

8 Experiment  Demonstrate how pain or perception of pain would affect function Overall Assumption  Craniofacial pain (CFP) and its effects on biting is a model for understanding acute/chronic pain in general  Pain will (may be) decrease the motor functions

9 Objective  To study the effect of pain in the masseter muscle and Temporomandibular Joint (TMJ) on biting ability / bite force  Sixteen healthy volunteers  Two sessions separated by 3-4 days  Experimental pain

10 Methods Biteforce

11 Results

12 Pain perception

13 Conclusion  Pain did not affect bite force  Individual’s reaction to pain would be dependent on the ability of the individual to cope with the painful stimulus,  Not pain in itself but rather how pain is perceived

14 Section of clinical oral physiology

15 FORSØG: SMERTENS INDFLYDELSE PÅ DET SENSORISKE SYSTEM 12 FRISKE DELTAGERE DET KOMMER TIL AT GØRE LIDT ONT, men KUN I KORT TID. HUSK: LUKKEDE ØJNE OG KONCENTRERE JER OM OPGAVEN 1. TAKTILE STIMULI/ TANDSTIKKER FØR (LUKKEDE ØJNE) 1 prik på læben HVOR MEGET KAN DU MÆRKE? O = KAN IKKE MÆRKE PRIKKET, 50 SMERTE STARTER og 100 VÆRST TÆNKLIG SMERTE. Alle tal på skalaen fra 0-100 må bruges. 2. SMØR forsigtigt en lille dråbe, svarende til vatpinden på læben. DELTAGERE: I MÅ IKKE SLIKKE DET AF! ;o) 3. PÅ SKALAEN 0-10 HVOR ONT GØR DET? 0 = INGEN SMERTE, 10 = VÆRST TÆNKELIG SMERTE HVILKET ORD HVIS NOGET BESKRIVER BEDST SMERTEN? ANDET SÅ SKRIV DET GERNE PÅ SEDDLEN 4. TAKTILE STIMULI/ TANDSTIKKER EFTER (LUKKEDE ØJNE) 1 prik på læben HVOR MEGET KAN DU MÆRKE? O = KAN IKKE MÆRKE PRIKKET, 50 SMERTE STARTER og 100 VÆRST TÆNKLIG SMERTE. Alle tal på skalaen fra 0-100 må bruges. 0……………..……50……...…..………100

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